A rare lay press article that gets everything right regarding Delta

Discussion in 'Coronavirus Pandemic Discussions' started by CenterField, Aug 5, 2021.

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  1. Bowerbird

    Bowerbird Well-Known Member

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    It is about viral load

    An unvaccinated person can build up a much much higher viral load than a vaccinated person just like being indoors where there is poor air conditioning with an infected person will ensure you are exposed to more virus than if you were outdoors and standing upwind. This is why it is such a crying tearing shame that masks became so politicised. With a combination of masking and vaccines we could really choke the spread of this thing
     
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  2. independentthinker

    independentthinker Well-Known Member

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    During mask mandates before, cases climbed. They did not fall. They never came back down until the vaccines were available. With Delta, it is over twice as contagious as the original variants, which means that cases would climb even faster under new mask mandates than the previous mask mandates. Also, there are a ton more "breakthrough" cases with Delta than before Delta. And breakthrough cases are very misleading because many of the vaccinated are spreading the virus, and they aren't actually diagnosed as breakthrough cases because they are not sick enough to be tested but are spreading Delta nonetheless and are not reported breakthrough cases.

    People are fooling themselves if they think Delta will get under control if we are all vaccinated and start wearing masks again. The only thing you can really argue is that with vaccines, there is a huge chance that if you get infected you won't wind up in the hospital or die. That's it and I admit, that's big. But, it is NOT unvaccinated people who are responsible for increasing cases and we are not going to get Delta case numbers down by being vaccinated and/or wearing masks. In fact, since there are more vaccinated people than unvaccinated people, the vaccinated are actually spreading Delta more than the unvaccinated are.
     
    Last edited: Aug 5, 2021
  3. Bowerbird

    Bowerbird Well-Known Member

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    And yet elsewhere in the world masks WORKED. Mind you the Australian experience has been to use a combination of short lockdowns, masks and effective contact tracing.

    https://www.abc.net.au/news/2021-08-06/nsw-covid-delta-outdoor-transmission-risk/100353394
     
  4. LangleyMan

    LangleyMan Well-Known Member

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    The "vaccine program," whatever that means, has "failed" in what way?
    Modify the vaccine. The alternative is what? Get it and develop immunity by getting it?
     
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  5. CenterField

    CenterField Well-Known Member Past Donor

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    I don't disagree with some of what you're saying. Yes, of course we (meaning, we the scientific community) knew very well it was aerosol transmission... and we were the ones who protested and pressured the WHO to recognize it.

    Yes, we won't reach herd immunity. Yes, we'll end up with endemic SARS-CoV-2.

    But no, you are CURRENTLY wrong about the amount of protection the vaccines yield against the Delta. It is blatantly wrong to say "vaccinations don't stop Delta, not one bit" - it contradicts the data.

    But yes, that protection may fall down any moment if additional variants of concern pop up, and they likely will. This an evolving situation, and it will change. WHEN it does, then maybe you'll be right about it, but it hasn't changed yet.

    Look, I don't think you'll believe me (although I know what I'm saying). Whatever. I think you are allowing yourself to be influenced by bombastic media that uses information selectively and in a distorted manner, rather than scientific data, but then, you're not alone in doing that. I have little hope that scientific facts will sway lay people who hear otherwise from distorted sources. So, be may guest, keep believing that the vaccines are impotent against the Delta, when they aren't.
     
  6. CenterField

    CenterField Well-Known Member Past Donor

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    All of the variants of concern. Look at my thread about the variants for a full explanation.
    http://www.politicalforum.com/index.php?threads/sars-cov-2-variants.584511/
    Having a mutation in the spike protein doesn't mean the vaccines become immediately useless. The spike protein is big and has several regions. The variants have multiple mutations. When they have a sufficient number of mutations in the spike protein (of course the virus has several other proteins, not just the spike) and these mutations enhance either infectiousness or lethality or antigenic drift or a combination of these, they get called variants of concern.
    Look especially at this post that names the mutations:
    http://www.politicalforum.com/index.php?threads/sars-cov-2-variants.584511/#post-1072472494
     
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  7. FreshAir

    FreshAir Well-Known Member Past Donor

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    the spikes are the viruses keys to the cell, if they change that much, the keys probably will no longer work

    it can happen, just less likely
     
    Last edited: Aug 5, 2021
  8. CenterField

    CenterField Well-Known Member Past Donor

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    Not really, the mutations are in order to facilitate the key to the cells (positive evolutionary trait). That's precisely why the new variants are more contagious. They adhere better to the ACE-2 receptors in the cells.

    There are mutations that go the other way around... and these viruses then don't survive and don't spread.

    The ones that are surging are the ones that have an advantage in infectiousness.
     
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  9. LangleyMan

    LangleyMan Well-Known Member

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    That they rose or fell is attributable to what factors--and why?
    You're saying masks cause an increase in transmission? Based on what?
    Speculation. How about some evidence?
    It will be under better control.
    So, how come almost everyone in hospital for covid is unvaccinated?
    You might think about this one.
     
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  10. CenterField

    CenterField Well-Known Member Past Donor

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    Holy freaking cow, we had 121,000 new cases today!!! This is going very, very poorly!!! The increase has been very sharp, and we're still in the summer with high temperatures. The way things are going, we'll be back to square zero in the fall and winter. The upward curve now is as sharply up as it was in November, so, we may be headed to a *huge* surge.

    Or not, there's been a drop in Europe, and we're delayed in regards to them, so, who knows? It's been harder and harder to predict things, these days. This virus is very unpredictable.

    Anyway, the virus is still showing that when people say "it's over" the virus is unimpressed.
     
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  11. FreshAir

    FreshAir Well-Known Member Past Donor

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    not really what? When they change enough that the vaccine no longer works? that has not happened yet, the odd are less that it will, but as I said... it could
     
  12. CenterField

    CenterField Well-Known Member Past Donor

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    "Not really," what you said about the spike mutating so much that the virus can't attach to cells. This does happen, but then that variant goes kaput. It's the ones that attach better to the cell, that is, the ones that have an evolutionary advantage, that take over. No, I didn't imply that they have changed enough already that the vaccine no longer works. If you follow my posting you'll see that I've been saying the opposite.
     
  13. Pro_Line_FL

    Pro_Line_FL Well-Known Member Past Donor

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    Yes, it sounds like we blew our chance and amazingly even now there are still community leaders (like governors) doing their best to stand in the way. For example Florida schools are banned from asking kids to wear masks. Its absurd. Lot of parents will not allow their kids to go to school knowing they'll come back crawling with viruses and potentially infect more vulnerable family members.
     
    Last edited: Aug 6, 2021
  14. independentthinker

    independentthinker Well-Known Member

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    I'm tellin ya:

    https://news.yahoo.com/israel-vaccinated-fast-looked-had-113759148.html?fr=sycsrp_catchall

    https://www.cnbc.com/2021/07/23/del...ective-in-israel-prevents-severe-illness.html
     
  15. FreshAir

    FreshAir Well-Known Member Past Donor

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    that is what I was saying, sounds like we are saying the same thing

    if the spike mutates too much that the vaccine doesn't work, it probably won't be able to enter the celll anymore, now as I said, it could, just less likely
     
  16. CenterField

    CenterField Well-Known Member Past Donor

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  17. CenterField

    CenterField Well-Known Member Past Donor

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    Again, you are not really understanding this.

    Months ago last time I checked, there were 300,000 mutations since the pandemic started.

    Most mutations don't do anything, or they confer a disadvantage, which then makes that strain go kaput.

    If a strain mutates BOTH to evade antibodies AND to have the spike protein so altered that it no longer adheres to the ACE-2 receptors, that mutated strain will last all of a couple of minutes until it dies out... so that is irrelevant. A strain that is not able to enter the cell anymore cannot replicate (viruses do not replicate outside cells) so it is a non-factor.

    What typically happens is that mutations that confer to the spike protein a BETTER ability to attach to the cells, are the ones that predominate and spread, like the Alpha and the Delta (because these mutations make them more infectious). These mutated strains may or may not ALSO have additional mutations that confer an antigenic drift, evading antibodies. It's not really the case for Alpha but is the case for Delta, which is why we say that Delta is Covid on steroids; both more infections and better equipped to re-infect and to evade vaccines.

    The variants of concern have in average 12 to 20 mutations in their spike proteins (and others elsewhere). Some of these mutations are very significant, some aren't. In my thread about the variants, I listed each mutation and its significance. Won't redo it here for lack of time but you can use the search function to get to that thread, searching the keyword variants as required to be in the title of the thread, and me as the author.
     
  18. independentthinker

    independentthinker Well-Known Member

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  19. independentthinker

    independentthinker Well-Known Member

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    https://www.yahoo.com/news/england-says-delta-infections-produce-105701728.html
     
  20. independentthinker

    independentthinker Well-Known Member

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    https://www.yahoo.com/news/england-says-delta-infections-produce-105701728.html
     
  21. independentthinker

    independentthinker Well-Known Member

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  22. independentthinker

    independentthinker Well-Known Member

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    https://www.yahoo.com/news/england-says-delta-infections-produce-105701728.html
     
  23. CenterField

    CenterField Well-Known Member Past Donor

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  24. Pro_Line_FL

    Pro_Line_FL Well-Known Member Past Donor

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    If you see a medical expert being interviewed in the media and he/she says you should take it, then you might want to listen. In the other hand, if you see a political panel offer opinions in the media, then you might want to take it with a grain of salt.

    Common sense.

    Discernment!
     
    Last edited: Aug 6, 2021
  25. FreshAir

    FreshAir Well-Known Member Past Donor

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    I understand, and your basically saying the same as I am

    I do not care about the mutations that can no longer cause us harm, so they don't really count
     

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