Repeal the 2d Amendment and crazy libs will want to repeal all the others... things like free speech anger them too.
I think we have a better shot at colonizing Pluto. Clearly. I would argue it's more cultural than related to laws as are poverty rates.
Murder rates across the U.S. largely correlate to racial demographics. But to a lower extent, also to areas with lots of "rednecks", again probably having something to do with the gene pool, but maybe also income level too. You can read American Nations by Colin Woodard, has a discussion on how much of the white population in many parts of the South (or the "upper South") originated from a separate gene pool from the rest of America.