New study - the SARS-CoV-2 persists in the body for months

https://assets.researchsquare.com/files/rs-1139035/v1_covered.pdf?c=1640020576

A new study released online Saturday, looking at autopsies of individuals who died from or merely with Covid, including mild and asymptomatic cases, found the virus in multiple organs, including and especially the brain, for up to 230 days after symptom onset,

While the "highest burden" of infection was in the lungs and airway, the study showed the virus can "disseminate early during infection and infect cells throughout the entire body," including in the brain, as well as in ocular tissue, muscles, skin, peripheral nerves and tissues in the cardiovascular, gastrointestinal, endocrine and lymphatic systems.

"Our data support an early viremic phase, which seeds the virus throughout the body following pulmonary infection," the researchers wrote.

All 44 autopsies they performed had these long-standing findings. All of them.

And to think that this is what anti-vaxxers prefer to get - a nasty virus (which has 29 proteins) everywhere in their organism for months, rather than a tiny dose of the virus' spike protein only...

So ironic.

 

Fascinating read and it is above my pay grade.
In layman terms, if someone has a comorbidity, then they most definitely should get the vaccine and booster?

(“95.5% of patients had at least one comorbidity, with hypertension (54.5%), obesity (52.3%), and
130 chronic respiratory disease (34.1%) being most common”)

 

What will you do when it's 10 years from now and the vaccine may have damaged your brain and or any of the following, ocular tissue, muscles, skin, peripheral nerves and tissues in the cardiovascular, gastrointestinal, endocrine and lymphatic systems? What about the companies that made the surgical mesh for hernias. I'm sure they didn't plan on a product doing that to the cost of multi millions. How long did it take for the makers of gramoxone herbicide to find out their product is linked to Parkinson's?

 

Does the study tell if these people were vaccinated or not?

 

I have to repeat this every time some one gives one of these examples. You only take the vaccine once a year in a tiny amount.
One contact a year with Gramoxone would not cause Parkinsons.
The reason most drugs go through long term trials is because you take them every day for a very long time.

 

This is insane, there were reports/studies earlier of course of how this virus was affecting multiple aspects, but the specifics of this report are breathtakingly unfathomable(though cross referenced through several studies.) If true, this is the world's deadliest virus in human history, capable of impacting the entire humanoid system simultaneously. Not even cancer can make that claim(at least not as rapidly.)

 

....And the surgical mesh?

 

Surgical mesh is an operation, not a drug. But to be fair to you it has proved to have issues with some users.
Science is not perfect, but I bet I can name more drugs that have worked and saved lives than you can name ones that have failed.
Lets set the ball rolling. There are approximately 2,000 prescription drugs in use at this time.

 

The bulk of these autopsies were done at a time when the vaccines were not yet available.

 

Yes, it's a very nasty virus. I've been trying to warn you all about it for months. I've been saying, it's not just death toll but organ damage. People largely ignore what I'm saying and anti-vaxxers continue to spew their nonsense and seem to prefer all this horrible organ damage to two or three tiny doses of something that degrades and leaves your organism in a couple of days, and they all whine about "long-term side effects" - none have been identified to date - while all this horrible long term presence of the virus in multiple organs doesn't seem to bother them. It is indeed insane, you said it well.

Certainly this virus is the most deadly that ever hit American, with the number of casualties being bigger than all others put together.

But I wouldn't say it's the worst ever to hit humankind. There are viruses even more aggressive such as Ebola. The issue is, Ebola is so aggressive that it kills most people it infects so it can't move so well among the population and the outbreak fizzles. But the SARS-CoV-2 has just the "right" combination of infectiousness + high potential for organ damage.

THAT's why health authorities all over the world took it darn serious, but over here, due to political play, people keep minimizing it and calling it a hoax or saying that the containment measures are an over-reaction.

I mean, there are people who compare this to the common cold. THE COMMON COLD!!!! It's insane.

 

Agreed. Just one thing: 2,000 in the US. More like 30,000 different ones, worldwide.
Not to forget the billions of people saved by vaccines (polio, measles, all the others).
Anti-vaxxers are insane.

 

Thanks CF that's a typo, I meant to type 20,000. Still not 30k, but 2k is very meagre.

 

Yes, I was thinking, always had the 30,000 in mind, did we restrict so much in later years? In my specialty we didn't but I don't know what is happening in other specialties. Likely growing more numerous rather than shrinking.

 

Ranitidine (Zantac) is associated with several forms of cancer, Found to spontaneously break down into the carcinogen.

 

Aciclovir (or acyclovir) is an antiviral medicine.

It treats infections caused by the herpes virus (herpes simplex).
Your turn.

 

Another comment about this same study:

https://www.mdedge.com/cardiology/a...ays-after-infection?ecd=WNL_new_211229_mdedge

“We don’t yet know what burden of chronic illness will result in years to come,” Raina MacIntyre, PhD, a professor of global biosecurity at the University of New South Wales, Sydney, told Bloomberg News.

“Will we see young-onset cardiac failure in survivors or early-onset dementia?” she asked. “These are unanswered questions which call for a precautionary public health approach to mitigation of the spread of this virus.”

 

It’s unlikely Covid vaccines will damage organs. Certainly much less likely to do damage than an infection. If you read the study you find this:

If we are finding virus all over in bodies of a demographic that was ill enough 80% were incubated, but not much direct damage to cells of the infected organs, we would not expect damage from the bit of antigen we produce after vaccination.

 

Right, but do realize that these are autopsy findings. The correlation between the presence of the virus in cytopathology / inflammation with clinical pictures, with the paucity of inflammation, may not hold true for the patients who get long Covid. These subjects in the study are people who died. So, if they had survived and the virus conserved a continuous presence (e.g. Long Covid) we might see more organ damage, with time. Once the subject dies, everything freezes up. If a patient dies of massive viral pneumonia, the virus may not have enough time to do damage elsewhere. The fact is that despite the paucity of inflammation in this study, in real life and in survivors, we've seen renal insufficiency, "brain fog" with cognitive impairment (I know it's hard to quantify without a full battery of neurocognitive tests pre- and post-Covid, but it does correlate with brain damage in other studies), we know of the heart issues with myocarditis and pericarditis, we've seen new onset diabetes due to destruction of beta cells in the pancreas, and so on and so forth. Sometimes the paucity of macroscopic and even microscopic damage does not rule out progressive functional impairment.

I do agree that we would not expect damage from the bit of antigen we produce after vaccination. That is preposterous as an argument, because like you said the vaccine produces a tiny bit of antigen (the S protein, one of 29 viral proteins in miniscule amount) while the virus produces massive amounts of antigens, including all 29 proteins and vastly bigger amounts of that same S protein.

"Oh, I don't want these antigens circulating in my body from the vaccine, so I'll jus risk getting the natural infection" must be one of the most boneheaded statements ever, fully worthy of the Darwin Award. That is, "To avoid a miniscule amount of 1 antigen, I'll get massive amounts of all 29 of them." LOL.

 

@557 I want to add the following. We've seen that often, the mechanism of death in the case of Covid-19 sort of splits between one of two (of course a patient can have both, but often it's not entirely the case as we see a predominance of one), and we call them phenotypes of that person's body's specific reaction to the infection. One phenotype is the pneumonia one. Such patients have massive viral pneumonia with lung consolidation and respiratory failure and may die this way, simply by not being able to oxygenate their bodies despite ventilation. Another phenotype is the inflammatory one. Such patients are the ones who present the infamous cytokine storm, and end up dying of multiple organ failure, not necessarily linked to respiratory failure (although the latter of course is not excluded).

So, if these autopsies found more pulmonary involvement than inflammatory involvement in other organs, it doesn't mean that the patients who do present a more inflammatory reaction are not out there. Actually the over-reaction of the immune system requires a bit of a stronger immune system, which may represent a phenotype that is different from the pneumonia one. Stronger but dysregulated, of course, which is one of the reasons why obesity is such a risk factor for severe Covid, given that as you know, the obese have a lot of trouble with cytokine regulation.

The study had 44 autopsies. It's conceivable that if they had focused on patients who died of a cytokine storm, they'd have found more widespread inflammatory changes in other organs.

 

The obese and hypertense are most likely the same group, which leaves roughly 2% of non-obese hypertense patients. Given that, it's reasonable to conclude that hypertension alone is probably not a significant risk factor - at least not nearly as significant as obesity and respiratory disease.

 

Incredible to think so many still don't grasp the latter. They're still trying to convince themselves that it's a coincidence, or a worldwide conspiracy. Anything to avoid confronting the reality, it seems. I can understand the powerful attraction to believing it's all BS, but it's concerning (to me, at least) to see that we've become so helpless in the face of unexpected challenge, that we'll engage in fantasy rather than adjust. We're so accustomed to certainty, safety, and predictability, that we appear to have lost our flight/fight reflexes.

 

I would agree if the study only looked at short term cases. But the study included people who died up to 230 days after testing positive. I believe the majority of long cases had virus in multiple tissues, but primarily the brain. Of course I agree after death no viral replication occurs, nor would virons be redistributed to other organs.

Well most people are going to get both eventually.

 

I’m glad you added this post. It is possible deaths from cytokine storm are underrepresented in the study. They were selected randomly though I believe, not based on respiratory symptoms/cause of death alone, correct?

 

It's like playing Russian roulette taking vaccines with no long term studys for side effects. The Pharmaceutical Companies have a free pass too. If something shows up in the future, you can't even sue them. The government granted them immunity. How nice.

 

It's like playing Russian roulette taking vaccines with no long term studys for side effects. The Pharmaceutical Companies have a free pass too. If something shows up in the future, you can't even sue them. The government granted them immunity. How nice.